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. 2010 Aug 17;172(7):781–789. doi: 10.1093/aje/kwq213

Appendix Table 2.

Median Generalized Impact Fraction and Attributable Fraction (With 2.5%–97.5% Simulation Intervals) for Heart Failure Derived From 10,000 Bootstrapped Data Sets Using the Case-Load Weighted-Sum Method, Given 10 Scenarios of Reduced Prevalence of Obesity and Overweight, Atherosclerosis Risk in Communities Study, 1987–2003

Scenario No. Hypothetical Weight Reduction Scenario Median Generalized Impact Fraction (× 100) 95% Simulation Interval
1 15% reduction in obesity, shift obese to overweight 2.9 2.3, 3.5
2 15% reduction in obesity, shift obese to normal weight 3.4 2.7, 4.0
3 15% reduction in obesity and overweight, shift both down 1 category 3.7 3.0, 4.5
4 15% reduction in obesity and overweight, shift both to normal weight 4.2 3.0, 5.4
5 30% reduction in obesity, shift obese to overweight 5.7 4.6, 7.0
6 30% reduction in obesity, shift obese to normal weight 6.7 5.4, 8.0
7 30% reduction in obesity and overweight, shift both down 1 category 7.4 6.0, 9.0
8 30% reduction in obesity and overweight, shift both to normal weight 8.5 6.1, 10.7
9 Complete elimination of obesity, shift to normal weight 22.0 18.0, 27.0
10 Complete elimination of obesity and overweight, shift to normal weight 28.0 20.0, 36.0