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. Author manuscript; available in PMC: 2011 Dec 16.
Published in final edited form as: Nature. 2010 Dec 16;468(7326):933–939. doi: 10.1038/nature09564

Table 1.

Association of S72N with anthropometric indices in the MACAD cohort

S/S (n=346) S/N (n=338) N/N (n=95) P value
Weight (kg) 73.3 (19.6) 75.1 (20.6) 76.0 (22.2) 0.033
BMI (kg/m2) 28.1 (6.1) 28.3 (6.1) 29.1 (5.6) 0.038
Hip circumference (cm) 103.0 (12.3) 104.5 (13.0) 104.5 (12.8) 0.033
Waist (cm) 90.5 (15) 93.0 (16) 93.3 (17.3) 0.15
BSA (m2) 1.77 (0.28) 1.81 (0.30) 1.84 (0.30) 0.075
Waist-hip-ratio 0.88 (0.10) 0.89 (0.11) 0.88 (0.12) 0.43

Values are median (interquartile range). Significant P values are in bold.

S/S: Individuals homozygous for wild-type CRTC3 (Ser72); S/N: Individuals heterozygous for variant CRTC3 (Asn72); N/N: Individuals homozygous for variant (Asn72) CRTC3.