. Author manuscript; available in PMC: 2011 Dec 16.

Published in final edited form as: Nature. 2010 Dec 16;468(7326):933–939. doi: 10.1038/nature09564

Table 3.

Association of S72N with anthropometric indices in the MACAD and MESA Mexican-American cohorts combined

	S/S or A/A (n=769)	S/N or A/G (n=787)	N/N or G/G (n=210)	P value
Weight (kg)	74.8 (20.2)	75.9 (20.6)	78.3 (20.2)	0.0039
BMI (kg/m²)	28.8 (5.7)	28.6 (6.2)	29.0 (6.0)	0.39
Hip circumference (cm)	103.5 (12.0)	103.5 (13.0)	104.0 (13.2)	0.037
Waist (cm)	97.0 (16.6)	97.2 (17.0)	97.9 (16.5)	0.22
BSA (m²)	1.79 (0.28)	1.81 (0.29)	1.85 (0.28)	0.0065
Waist-hip-ratio	0.94 (0.12)	0.94 (0.11)	0.95 (0.11)	0.049

Values are median (interquartile range). Significant P values are in bold.

S/S or A/A: Individuals homozygous for wild-type Ser72 at rs8033595 or of A/A genotype at rs3862434; S/N or A/G: Individuals heterozygous at rs8033595 or at rs3862434; N/N or G/G: Individuals homozygous for variant rs8033595 (Asn72) or of G/G genotype at rs3862434. rs8033595 (S72N) was genotyped in MACAD subjects; the perfect proxy rs3862434 was genotyped in MESA.