Table I.
Clinical and virological characteristics of HCC and non-HCC patients
| Characteristic | HCC (n = 152) | Non-HCC (n = 136) | P value |
| Age, mean ± SD | 47.9 ± 11.9 | 45.6 ± 11.4 | Matched |
| Sex, male (%) | 130 (85.5) | 122 (89.7) | Matched |
| ALT (U/L), mean ± SD | 59.9 ± 29.5 | 70.4 ± 66.2 | 0.075 |
| HBeAg positive (%) | 49 (32.2) | 28 (20.6) | 0.026 |
| HBV DNA (log copies/ml), mean ± SD | 3.7 ± 1.0 | 4.4 ± 1.0 | <0.001 |
| Genotype (%) | |||
| B | 17 (11.2) | 9 (6.6) | 0.177 |
| C | 132 (86.8) | 123 (90.4) | 0.338 |
| Others | 3 (2.0) | 4 (2.9) | 0.595 |
| Mutation in box α | |||
| T1653 (%) | 53 (34.9) | 34 (25.0) | 0.069 |
| Mutations in basal core promoter (%) | |||
| V (not T) 1753 | 43 (28.3) | 20 (14.7) | 0.005 |
| T1762 | 114 (75.0) | 92 (67.6) | 0.167 |
| A1764 | 131 (86.2) | 110 (80.9) | 0.224 |
| T1762/A1764 | 111 (73.0) | 91 (66.9) | 0.258 |
| T1766 | 29 (19.1) | 19 (14.0) | 0.246 |
| A1768 | 21 (13.8) | 11 (8.1) | 0.123 |
ALT, alanine aminotransferase.