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. Author manuscript; available in PMC: 2011 Jan 24.
Published in final edited form as: Clin Cancer Res. 2008 Jul 1;14(13):4345–4352. doi: 10.1158/1078-0432.CCR-07-5282

Table 5.

FPRP for significant associations of NEIL2 g.4102971 and SCCOOP

Subgroup Positive OR95%CI* P OR Statistical power§ Prior probability
0.25 0.1 0.01 0.001 0.0001
All participants 1.27 (1.01–1.60) 0.044 1.2 0.69 0.16 0.36 0.86 0.98 1.00
Current alcohol users 1.71 (1.19–2.45) 0.003 1.7 0.51 0.02 0.05 0.38 0.86 0.98
Oropharynx cancers 1.36 (1.05–1.76) 0.02 1.3 0.63 0.09 0.22 0.76 0.97 1.00
T2 1.41 (1.04–1.93) 0.028 1.4 0.53 0.14 0.32 0.84 0.98 1.00
T3 1.58 (1.06–2.35) 0.023 1.5 0.6 0.10 0.25 0.79 0.97 1.00
N2 1.35 (1.02–1.80) 0.036 1.3 0.61 0.15 0.35 0.85 0.98 1.00
N3 2.53 (1.27–5.03) 0.007 2.5 0.51 0.04 0.10 0.56 0.93 0.99
N2,3 or T3,4 1.33 (1.03–1.72) 0.027 1.3 0.58 0.12 0.29 0.82 0.98 1.00
*

OR 95% CI calculated from the study sample by univariate logistic regression analysis.

P value calculated by the χ2 test in comparisons of genotype distributions in cases and controls.

OR was the odds ratio closest to the observed odds ratio in each stratified subgroup used to calculate FPRP.

§

Statistical power was calculated using the number of observations in the subgroup and the OR and P values in this table.