Table 4.
Depression Predictor | No. of Studies | Unadjusted Pooled RR (95% CI)a | No. of Missing Studies | Trim-and-Fill Adjusted Pooled RR (95% CI)b |
---|---|---|---|---|
PTB | ||||
Overall | 20 | 1.13 (1.06–1.21) | 10 | 1.07 (0.99–1.15) |
Categorical | 16 | 1.39 (1.19–1.61) | 6 | 1.24 (1.04–1.47) |
Continuous | 4 | 1.03 (1.00–1.06) | 1 | 1.03 (1.00–1.07) |
LBWc | ||||
Overall | 11 | 1.18 (1.07–1.30) | 6 | 1.10 (1.00–1.22) |
Categorical | 9 | 1.49 (1.25–1.77) | 4 | 1.34 (1.10–1.64) |
IUGR | ||||
Overall | 12 | 1.03 (0.99–1.08) | 4 | 1.03 (0.97–1.09) |
Categorical | 8 | 1.45 (1.05–2.02) | 3 | 1.17 (0.82–1.68) |
Continuous | 4 | 1.02 (1.00–1.04) | 2 | 1.00 (0.98–1.03) |
Abbreviations: CI, confidence interval; IUGR, intrauterine growth restriction; LBW, low birth weight; PTB, preterm birth; RR, relative risk.
Using random-effects models.
Using random-random effects trim-and-fill models.
Only 2 studies used a continuous depression predictor; the trim-and-fill algorithm requires 3 or more studies.