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. Author manuscript; available in PMC: 2012 Jan 21.
Published in final edited form as: J Mol Biol. 2010 Nov 2;405(3):642–652. doi: 10.1016/j.jmb.2010.10.041

Figure 1.

Figure 1

POLQ constructs used in this study. Full length POLQ is shown on top as a 2590 amino acid sequence containing an N-terminal helicase-like domain, a large central domain and a C-terminal A-family polymerase domain. The N-terminal amino acid and level of polymerase activity are shown for each of the five truncation constructs. The truncation mutant QM is enlarged to show the relative location of the three insertion elements and their predicted location relative to the functional domains of Taq pol I. The positions of the insertions are exactly as previously described.19 The equivalent position of the chaos1 mutation is also indicated. The amino acid sequences of the loop deletions are shown in italics within their respective flanking sequences.