Table 1. Total number of births in EUROCAT registry areas in 2000–2005; number and prevalence of sex chromosomal trisomy cases, percentage prenatally diagnosed, median gestational age at diagnosis and percentage of prenatally diagnosed cases resulting in termination of pregnancy.
| Country | EUROCAT register(s) | Number of births in EUROCAT registry areas 2000–2005 | Total cases sex chromosome trisomy | Prevalence all sex chromosomal trisomies per 10 000 births (95% confidence intervals) | % Cases PD | Median GA at diagnosis | % Cases of PD ending in TOPFA |
|---|---|---|---|---|---|---|---|
| Austria | Styria | 62 667 | 8 | 1.28 (0.64–2.55) | 100 | 15 | 13 |
| Belgium | Antwerp, Hainaut | 182 467 | 38 | 2.08 (1.52–2.86) | 79 | 16 | 27 |
| Denmark | Odense | 32 003 | 5 | 1.56 (0.65–3.75) | 60 | 11 | 67 |
| England and Wales | E Mid and S York, Northern England, Thames Valley, Wales, Wessex | 951 001 | 121 | 1.27 (1.07–1.52) | 79 | 16 | 27 |
| France | Paris, Strasbourg | 272 618 | 84 | 3.08 (2.49–3.82) | 98 | 17 | 38 |
| Germany | Saxony-Anhalt | 106 257 | 18 | 1.69 (1.07–2.69) | 78 | 15 | 43 |
| Italy | Emilia Romagna, Tuscany | 343 971 | 92 | 2.67 (2.18–3.28) | 97 | 16 | 46 |
| Poland | Wielkopolska | 206 170 | 4 | 0.19 (0.07–0.52) | 50 | 21 | 0 |
| Portugal | Southern Portugal | 113 310 | 18 | 1.59 (1.00–2.52) | 100 | 18 | 44 |
| Spain | Barcelona, Basque Country | 164 864 | 54 | 3.28 (2.51–4.28) | 95 | 16 | 44 |
| Switzerland | Vaud | 42 874 | 23 | 5.36 (3.57–8.07) | 96 | 17 | 23 |
| Total | 2 478 202 | 465 | 1.88 (1.71–2.06) | 89 | 16 | 36 |
Abbreviations: E Mid, East Midlands; EUROCAT, European Surveillance of Congenital Anomalies; GA, gestational age; PD, prenatal diagnosis; S York, South Yorkshire; TOPFA, termination of pregnancy for fetal anomaly.