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. Author manuscript; available in PMC: 2011 Jan 24.
Published in final edited form as: Am J Reprod Immunol. 2010 Mar 29;63(6):587–600. doi: 10.1111/j.1600-0897.2010.00848.x

Table I.

Toll-like receptors (TLRs) and ligands

Ligands
TLR Exogenous Endogenous
TLR1 Triacetylated lipoproteins (witn TLR2)
TLR2 Peptidoglycan, Lipopeptides, Lipoteichoic acids, Zymosan
TLR3 Double-stranded RNA Host RNA
TLR4 Lipopolysaccharides, paclitaxel Hsp60, Hsp70, Hsp90, ROS, HMGB1,Surfactant protein A, Fibrinogen, Fibronectin, Hyaluronic acid oligosaccharides, Eosinophil derived neurotoxin
TLR5 Flagellin
TLR6 Diacylated lipoprotein (with TLR2)
TLR7 Single-stranded RNA
TLR8 Single-stranded RNA
TLR9 Non-methylated CpG DNA, Herpes virus Autoimmune chromatine-IgG complex
TLR10 –