Table 4.

Association of AGT genotype and renal plasma flow.

SNP	Location	Ref. allele	Low Salt	Low Salt + AII	High Salt	High Salt + AII
rs11122580	−1178	G	0.019	0.013	-	0.003
rs2071404	−1074	T	0.019	0.013	0.050	0.003
rs2071406	−775	C	-	-	-	-
rs5046	−532	T	-	-	-	0.003
rs5049	−217	A	0.047	0.042	-	0.003
rs5050	−20	C	-	-	-	-
rs5051	−6	A	-	-	-	-
rs2493134	507	G	-	-	-	-
rs7539013	698	A	-	-	-	-
rs2004776	1164	A	0.019	0.033	-	0.039
rs4762	3889	T	-	-	-	-
rs699	4072	C	-	-	-
rs6687360	4874	A	-	-	-	-
rs2478543	5556	G	-	-	-	-
rs3789671	6066	A	0.041	-	-	0.028
rs3789670	6152	A	0.022	0.018	0.036	<10⁻⁴^*
rs3789669	6233	C	0.048	-	-	-
rs2493132	6309	G	-	-	-	-
rs3789667	6420	T	-	-	-	-
rs3827749	8307	T	-	-	-	-
rs2478523	8357	C	-	-	-	-
rs11122575	9597	C	-	-	-	-
rs7079	11525	A	-	-	-	-
rs943580	12822	C	-	-	-	-

All p-values are for linear regression of measured renal plasma flow (mL/min) and AGT genotype with age, sex, BMI, and collection location as covariates; only p-values <= 0.05 are shown

Value is significant with Bonferroni correction for multiple comparisons.

Minimum individuals were n = 180 low-sodium and n = 219 high-sodium; All, infused-angiotensin II.