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Skp2 siRNA inhibited the proliferation of PFC and NFC in vivo. Hematoxylin and eosin staining was performed to examine the histological changes 14 days after transfection. Obvious PFC and NFC proliferation was detected in pSuppressor vehicle group or without transfection (A, D, B, E). There was little PFC and NFC proliferation in Skp2 siRNA transfection group (C, F). Scale bar is equal to 20 μm.
