Table 3.
Logistic regression models for waist circumference (Waist_C), body mass index (BMI25), fasting triglyceride (Triglyc_C) and LDL cholesterol (LDL_C) concentration in blood
| Tested variable | Predictor variables | OR (95% CI) | p |
|---|---|---|---|
| Waist circumference (Waist_C): | Sex (males are referent) | 3.122 (1.475 - 6.607) | 0.003 |
| 1 = < 80 cm (F), < 94 cm (M); | Age (younger than 50 yrs are referent) | 0.728 (0.349 - 1.517) | 0.397 |
| 2 = ≥ 80 cm (F), ≥ 94 cm (M) | E2 allele of APOE gene (persons who do not have the genotypes: E2E3 or E2E4 are referent) | 3.301 (1.254 - 8.688) | 0.016 |
| -2 Log Likelihood = 198.021; Cox & Snell R2 = 0.251; Nagelkerke R2 = 0.344 | Glucose in blood (mmol/L) | 1.959 (1.234 - 3.112) | 0.004 |
| Triglyceride in blood (mmol/L) | 1.359 (1.043 - 1.770) | 0.023 | |
| LDL cholesterol in blood (mmol/L) | 1.583 (1.043 - 2.403) | 0.031 | |
| HDL_C (>1.0 (M) and >1.2 (F) are referent) | 5.505 (1.542 - 19.650) | 0.009 | |
| Body mass index (BMI25): | Sex (males are referent) | 1.027 (0.506 - 2.086) | 0.940 |
| 1 = BMI < 25; | Age (years) | 0.979 (0.955 - 1.003) | 0.080 |
| 2 = BMI ≥ 25 | E2 allele of APOE gene (persons who do not have the genotypes: E2E3 or E2E4 are referent) | 3.547 (1.471 - 8.557) | 0.005 |
| -2 Log Likelihood = 231.095; Cox & Snell R2 = 0.181; Nagelkerke R2 = 0.242 | Glucose in blood (mmol/L) | 1.323 (0.964 - 1.816) | 0.083 |
| Triglyceride in blood (mmol/L) | 1.309 (1.041 - 1.646) | 0.021 | |
| LDL cholesterol in blood (mmol/L) | 2.031 (1.369 - 3.014) | 0.000 | |
| HDL_C (>1.0 (M) and >1.2 (F) are referent) | 4.041 (1.521 - 10.737) | 0.005 | |
| Triglyceride concentration (Triglyc_C): | Sex (males are referent) | 1.345 (0.702 - 2.578) | 0.372 |
| 1 = triglyceride concentration < 1.7 mmol/L; | Age (younger than 50 yrs are referent) | 1.678 (0.911 - 3.091) | 0.097 |
| 2 = triglyceride concentration ≥ 1.7 mmol/L | E3_55 (persons who do not have the combination: | ||
| -2 Log Likelihood = 241.753; Cox & Snell R2 = 0.095; Nagelkerke R2 = 0.127 | E3 (APOE) + 55 (eNOS) are referent) | 0.396 (0.199 - 0.785) | 0.008 |
| BMI (kg/m2) | 1.046 (0.992 - 1.103) | 0.094 | |
| Index (= LDH/HDL) | 1.337 (0.922 - 1.938) | 0.125 | |
| LDL cholesterol concentration (LDL_C): | Sex (males are referent) | 2.682 (1.155 - 6.226) | 0.022 |
| 1 = LDL concentration < 3.0 mmol/L; | Age (younger than 50 yrs are referent) | 2.428 (1.024 - 5.760) | 0.044 |
| 2 = LDL concentration ≥ 3.0 mmol/L | E3_55_II (persons who do not have the combination: | ||
| -2 Log Likelihood = 144.692; Cox & Snell R2 = 0.132; Nagelkerke R2 = 0.220 | 0.302 (0.112 - 0.815) | 0.018 | |
| E3 (APOE) + 55 (eNOS) + II (ACE I/D) are referent) BMI (kg/m2) | 1.153 (1.058 - 1.256) | 0.001 | |