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. 2010 Apr 9;13(7-8):495–503. doi: 10.1159/000294469

Table 1.

Adjusted prevalence1 of family history of breast, colorectal, prostate, and lung cancers by respondent characteristics

Respondent characteristics Sample size lst-degree relatives
2nd-degree relatives
All relatives
# with positive family history prevalence, % (95% CI) # with positive family history prevalence, % (95% CI) # with positiv« family history : prevalence, % (95% CI)
Breast cancer
All2 1,015 114 10.9(8.8, 13.3) 194 17.9(15.4, 20.1) 281 26.4 (23.3, 29.8)
Gender§
 Female 622 69 11.2(8.2, 14.2) 142 23.0(18.9, 27.1) 192 31.0(26.5, 35.5)
 Male 393 45 10.5(7.2, 13.8) 52 12.6 (9.1, 16.2) 89 21.5(16.8, 26.2)
p = 0.77 p = 0.0007 p = 0.007
Race
 Non-Hispanic white only 877 107 11.6(9.0, 14.1) 173 18.4(15.7, 21.2) 254 27.6(24.1, 31.0)
 Non-Hispanic black only 48 1 4.8 (2.5, 7.2) 8 15.6(3.8, 27.5) 8 15.4(3.6, 27.3)
 Hispanic 40 3 11.2(0, 25.1) 4 5.3 (0, 10.8) 7 15.4(2.5, 28.3)
 Other 50 3 4.9(0, 11.6) 9 22.5 (7.8, 37.2) 12 27.2(12.1, 42.3)
p = 0.02 p = 0.13 p = 0.27
Age
 25–34 174 10 7.5 (2.8, 12.2) 37 17.4(11.2, 23.6) 45 24.3(16.9, 31.6)
 35–44 283 20 8.2(4.5, 11.8) 52 20.2(15.2, 25.3) 69 27.0(21.8, 32.3)
 45–54 355 50 13.3(9.3, 17.3) 70 16.4(12.6, 20.3) 104 25.8(20.4, 31.2)
 55–64 203 34 16.3(10.9, 21.7) 35 16.8 (11.2, 22.3) 63 28.9(21.8, 36.0)
p = 0.03 p = 0.62 p = 0.34
Education
 High school or less 198 21 9.3 (4.2, 14.3) 29 14.1 (8.7, 19.5) 45 21.4(14.5, 28.4)
 Some college or college graduate 582 62 11.0(7.9, 14.1) 115 17.8(14.7, 21.0) 162 26.2 (22.2, 30.3)
 Post-graduate 235 31 12.0 (7.3, 16.7) 50 21.5 (15.1, 27.9) 74 31.1 (24.4, 37.7)
p = 0.38 p = 0.14 p = 0.08
History of cancer
 Yes 95 12 10.7(3.1, 18.2) 15 14.0(6.9, 21.2) 25 23.4(14.2, 32.7)
 No 920 102 10.9(8.7, 13.1) 179 18.3(15.5, 21.1) 256 26.7(23.3, 30.1)
p = 0.96 p = 0.34 p = 0.54
Income3
 20,000 or less 97 11 17.7(2.9, 32.5) 16 17.4 (6.9, 28.0) 24 32.1(17.0, 47.1)
 20,001–40,000 142 10 8.8 (2.6, 14.9) 25 14.5 (8.4, 20.6) 33 21.4(13.6, 29.3)
 40,001–60,000 163 15 10.5(5.4, 15.6) 28 19.0(11.4, 26.6) 39 26.1 (17.7, 34.5)
 60,001–80,000 174 19 8.8 (4.4, 13.2) 36 18.4(12.8, 24.0) 49 24.5(18.7, 30.4)
 More than 80,000 359 47 10.9(7.6, 14.1) 72 17.8(13.2, 22.4) 111 27.1 (21.6, 32.7)
 Don't know/refuse 80 12 13.2(5.6, 20.7) 17 20.8(10.9, 30.7) 25 30.2(18.5, 41.9)
p = 0.57 p = 0.71 p = 0.99

Colorectal cancer
All2 1,015 66 5.1(3.9, 6.7) 133 12.3(10.4, 14.6) 186 16.5(14.2, 19.2)
Gender§
 Female 622 42 5.5 (3.6, 7.4) 92 15.1 (12.0, 18.3) 124 18.9(15.5, 22.3)
 Male 393 24 4.7 (2.6, 6.8) 41 9.6 (6.7, 12.4) 62 14.0(10.4, 17.5)
p = 0.65 p = 0.02 p = 0.05
Race
 Non-Hispanic white only 877 60 5.0 (3.6, 6.4) 125 13.6(11.2, 16.0) 172 17.5(14.7, 20.3)
 Non-Hispanic black only 48 1 3.3(1.1, 5.5) 5 7.0 (0.4, 13.5) 6 9.6 (0.2, 19.0)
 Hispanic 40 2 6.7(0, 17.1) 2 3.6 (0, 9.3) 4 9.2 (0, 19.5)
 Other 50 3 8.1 (0, 18.5) 1 3.0(1.4, 4.6) 4 10.7(0.3, 21.1)
p = 0.59 p < 0.0001 p = 0.44
Age§
 25–34 174 5 2.3(0.1, 4.5) 20 10.3(5.5, 15.2) 24 12.7(7.2, 18.3)
 35–44 283 9 3.0(1.1, 4.9) 37 13.8(9.7, 17.9) 44 15.8(11.2, 20.5)
 45–54 355 32 7.6 (4.6, 10.7) 52 11.9(8.3, 15.5) 76 17.3(12.8, 21.9)
 55–64 203 20 9.0 (4.7, 13.3) 24 13.3(7.6, 19.1) 42 21.2(14.9, 27.5)
p = 0.002 p = 0.49 p = 0.02
Education
 High school or less 198 11 4.0(0.9, 7.1) 22 10.9 (5.5, 16.2) 29 12.8 (7.2, 18.4)
 Some college or college graduate 582 39 5.8 (3.9, 7.7) 73 12.1 (9.5, 14.7) 107 17.0(13.8, 20.2)
 Post-graduate 235 16 4.4(1.9, 6.9) 38 14.4(8.9, 19.8) 50 17.9(11.6, 24.3)
p = 0.73 p = 0.34 p = 0.42
History of cancer
 Yes 95 9 6.3(1.5, 11.1) 13 12.5 (4.7, 20.2) 20 17.0(9.1, 24.9)
 No 920 57 5.0 (3.6, 6.4) 120 12.4(10.2, 14.6) 166 16.5(13.8, 19.1)
p = 0.61 p = 0.98 p = 0.89
Income3
 20,000 or less 97 4 2.5 (0, 5.6) 7 9.1 (2.0, 16.1) 10 10.4(3.1, 17.7)
 20,001–40,000 142 4 2.2 (0, 4.6) 16 9.5 (4.0, 14.9) 19 10.6 (5.2, 15.9)
 40,001–60,000 163 13 6.0 (2.7, 9.2) 20 10.9(4.3, 17.6) 31 15.9(9.1, 22.8)
 60,001–80,000 174 9 4.2(1.2, 7.2) 25 14.0 (7.7, 20.4) 34 18.3(11.1, 25.4)
 More than 80,000 359 27 5.8 (3.5, 8.0) 51 12.6(9.3, 15.9) 73 17.5(13.5, 21.4)
 Don't know/refuse 80 9 8.9 (2.5, 15.3) 14 17.6(7.8, 27.5) 19 23.1 (12.8, 33.4)
p = 0.14 p = 0.27 p = 0.06

Prostate cancer
All2 1,015 73 7.0 (5.2, 9.4) 83 8.0 (6.4, 9.9) 135 13.2(10.8, 16.2)
Gender§
 Female 622 47 7.2(5.1, 9.4) 61 11.3(8.4, 14.1) 95 15.9(12.6, 19.2)
 Male 393 26 6.8(3–1, 10.5) 22 5.3 (3.1, 7.6) 40 10.5 (6.7, 14.3)
p = 0.85 p = 0.03 p = 0.04
Race§
 Non-Hispanic white only 877 66 7.2 (4.9, 9.5) 77 8.2 (6.3, 10.2) 122 13.6(10.7, 16.4)
 Non-Hispanic black only 48 1 1.2 (0.5, 1.9) 0 1 1.1 (0.4, 1.7)
 Hispanic 40 1 1.1 (0.4, 1.7) 4 11.9(0, 25.3) 5 12.5(0, 25.6)
 Other 50 5 14.0(0.1, 27.9) 2 7.0 (0, 17.7) 7 20.5 (4.6, 36.5)
p< 0.0001 p = 0.86 p < 0.0001
Age
 25–34 174 3 4.1 (0, 10.6) 14 7.5(3.7, 11.4) 17 11.2(4.2, 18.3)
 35–44 283 19 6.6 (3–5, 9.8) 18 6.8 (3.7, 10.0) 34 12.2 (7.8, 16.6)
 45–54 355 30 8.7 (5.4, 12.0) 38 11.7(7.4, 15.9) 56 16.4(11.6, 21.2)
 55–64 203 21 9.3 (5.2, 13.4) 13 6.9(2.4, 11.5) 28 13.0(7.4, 18.6)
p = 0.30 p = 0.73 p = 0.65
Education
 High school or less 198 13 5.4(1.7, 9.0) 10 6.1 (0.7, 11.4) 22 11.0(4.3, 17.6)
 Some college or college graduate 582 41 7.4 (4.6, 10.2) 51 8.4 (5.9, 10.9) 79 13.6(9.9, 17.3)
 Post-graduate 235 19 7.3(3–6, 11.0) 22 9.9 (5.4, 14.3) 34 14.0(8.8, 19.1)
p = 0.62 p = 0.55 p = 0.71
History of cancer
 Yes 95 8 8.9 (2.4, 15.4) 11 11.6(3.3, 19.8) 17 17.7(8.1, 27.3)
 No 920 65 6.8 (4.8, 8.9) 72 8.0 (6.2, 9.8) 118 12.8(10.3, 15.3)
p = 0.50 p = 0.37 p = 0.24
Income3
 20,000 or less 97 5 6.5 (0, 14.6) 2 3.5(0, 9.1) 7 9.0 (0.2, 17.9)
 20,001–40,000 142 10 6.7(1.6, 11.9) 12 9.0 (2.7, 15.3) 21 14.3 (5.6, 23.0)
 40,001–60,000 163 8 4.3 (0.9, 7.8) 7 5.0(1.5, 8.5) 14 8.0 (4.0, 12.1)
 60,001–80,000 174 17 11.2(2.3, 20.0) 26 16.0(10.1, 21.9) 34 22.3(13.0, 31.7)
 More than 80,000 359 24 5.7(3.1, 8.2) 32 7.6 (4.5, 10.7) 48 11.8(7.8, 15.7)
 Don't know/refuse 80 9 10.3 (3.1. 17.4) 4 5.4(0.1, 10.7) 11 13.0(5.3, 20.6)
p = 0.96 p = 0.27 p = 0.48

Lung cancer
All2 1,015 75 6.4 (4.9, 8.3) 190 18.3(15.7, 21.2) 244 22.9 (20.4, 25.7)
Gender
 Female 622 49 6.4 (4.2, 8.7) 123 20.1(16.6, 23.6) 156 24.1(20.6, 27.6)
 Male 393 26 6.3 (3.8, 8.8) 67 16.4(12.1, 20.7) 88 21.7(17.3, 26.1)
p = 0.95 p = 0.21 p = 0.43
Race
 Non-Hispanic white only 877 61 5.6 (4.0, 7.3) 174 19.6(16.6, 22.6) 215 23.2 (20.3, 26.0)
 Non-Hispanic black only 48 4 12.8 (0, 27.5) 5 13.9 (0, 30.7) 9 26.0 (7.1, 44.9)
 Hispanic 40 5 8.3 (0, 16.7) 2 3.5 (0, 9.4) 7 12.4(1.0, 23.8)
 Other 50 5 11.1(1.2, 21.1) 9 16.0(37, 28.2) 13 25.8(11.4, 40.1)
p = 0.43 p = 0.56 p = 0.50
Age
 25–34 174 5 2.6 (0, 5.3) 40 25.2(17.9,32.5) 43 25.8(18.5,33.1)
 35–44 283 19 6.4 (3.4, 9.4) 52 19.5(13.9,25.0) 64 23.4(17.6,29.1)
 45–54 355 37 12.4(7.9,17.0) 71 17.4(12.8,22.1) 97 25.7(20.3,31.1)
 55–64 203 14 5.2(1.9,8.5) 27 9.5 (5.4, 13.6) 40 14.2 (9.0, 19.4)
p = 0.10 p = 0.006 p = 0.10
Education
 High school or less 198 19 7.9 (3.7, 12.2) 33 20.9(12.7,29.2) 48 27.3(18.6,36.1)
 Some college or college graduate 582 46 7.1(5.0,9.3) 107 16.7(13.6, 19.8) 139 21.8(18.7,24.9)
 Post-graduate 235 10 2.8 (0.8, 4.8) 50 20.6(14.4,26.8) 57 22.5(16.5,28.6)
p = 0.06 p = 0.90 p = 0.61
History of cancer
 Yes 95 10 8.4(3.0, 13.9) 19 18.7(9.9,27.6) 27 26.1 (16.9, 35.4)
 No 920 65 6.2 (4.5, 7.9) 171 18.3(15.4,21.1) 217 22.7(19.8,25.5)
p = 0.38 p = 0.92 p = 0.50
Income3
 20,000 or less 97 7 4.6 (0.6, 8.5) 11 9.7 (2.3, 17.2) 16 12.4(4.7,20.1)
 20,001–40,000 142 19 12.3 (5.2, 19.4) 28 16.9(10.5,23.3) 42 26.3(19.0,33.6)
 40,001–60,000 163 15 9.4(4.7, 14.1) 28 17.8(11.2,24.4) 37 22.7(15.6,29.8)
 60,001–80,000 174 9 3.7(1.0,6.3) 39 21.3(14.4,28.1) 47 25.2(18.1,32.2)
 More than 80,000 359 22 5.5 (2.8, 8.2) 72 19.7(14.4,25.1) 88 24.2(18.7,29.8)
 Don't know/refuse 80 3 2.9 (0, 6.4) 12 16.2 (7.9, 24.4) 14 17.9(8.2,27.7)
p = 0.22 p = 0.14 p = 0.25
1

Adjusted using logistic regression with all of the variables in the table included as covariates.

2

Overall prevalence is unadjusted.

3

Don't know/refuse group was not included in models for trend.

Global Wald F test for nominal variables and trend test for ordinal variables, p value for FDR ≤0.05.

Global Wald F test for nominal variables and trend test for ordinal variables, p value for SDR ≤0.05.

§

Global Wald F test for nominal variables and trend test for ordinal variables, p value for F/SDR ≤0.05.