Figure 4. Comparison of the mean methylation proportion and approximate position of informative CpG sites in the range of −400 to +200 according to the recognition sites of the transcription factors in the 10 candidate genes.

A) Comparison of methylation proportion in 36 plasma samples of breast cancer patients and 30 plasma samples of normal subjects. B) Comparison of methylation proportion in 60 triple samples (cancerous breast tissue, matched normal tissue and serum samples) from 20 breast cancer patients. (Dots in the map are corresponding to the mean methylation quantity of each CpG site in all analyzed cases).