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. 2011 Jan 24;6(1):e14575. doi: 10.1371/journal.pone.0014575

Figure 2. Koshu GSE protects dendrite processing of cultured hippocampal neurons exposed to a toxic concentration of glutamate.

Figure 2

(A) Representative image of untreated hippocampal neurons at 8 DIV immunostained for MAP2. Bar, 100 µm. (B) Representative binary images of cultured hippocampal neurons immunostained for MAP2 with no treatment or after a 30 min treatment with 50 µM glutamate alone, 50 µM glutamate plus 1.0 ng/ml KOS, or 50 µM glutamate plus 1.0 ng/ml MBA. Bar, 100 µm. (C) Quantification of the mean dendrite length by morphometric analysis (n = 10). ***, P<0.001 versus untreated controls.