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. 2011 Jan 10;18(1):3. doi: 10.1186/1423-0127-18-3

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Copyright ©2011 Lin et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Potency and safety of DNA demethylating agents. (A) Comparison of the dose-dependent suppressive effects of 5-Aza, procainamide, IM25, and IM9 on the viability of MCF7 cells by MTT assays. Columns, mean (n = 3); error bars, S.D. (B) Parallel ELISA analysis of the suppressive effects on EGFP expression in the two-component reporter system. Columns, mean (n = 3); error bars, S.D. (C) Western blot analysis of the effects of procainamide, 5-Aza, IM9, and IM25, each at 7.5 μM, on EGFP expression.