Table 2.
Evolutionary relationship along ORF of HRV-CU072 compared with the most closely matched N4 strain.
| Structural proteins | Nonstructural proteins | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Viral protein | VP4 | VP2 | VP3 | VP1 | 2A | 2B | 2C | 3A | 3B | 3C | 3D |
| Variation (nt) | 55 | 209 | 176 | 213 | 81 | 63 | 316 | 59 | 20 | 139 | 397 |
| Nucleotide variation (nt%) | 27 | 26 | 25 | 26 | 19 | 21 | 32 | 26 | 30 | 25 | 29 |
| Amino acid variation (aa%) | 14 | 31 | 25 | 23 | 16 | 19 | 26 | 12 | 23 | 16 | 24 |
| NS variation (aa) | 9 | 80 | 56 | 63 | 23 | 19 | 34 | 9 | 5 | 29 | 70 |
| NS variation (%) | 19 | 58 | 42 | 44 | 41 | 43 | 19 | 20 | 36 | 25 | 30 |
| NC-NS variation (%NC) | 33 | 40 | 38 | 29 | 48 | 21 | 44 | 33 | 40 | 14 | 30 |
NS = nonsynonymous, NC = nonconservative amino acid