Table 2.
Incidence of Suicidal Behavior or Ideation by Treatment Group and Subgroup in the Major Depressive Disorder Population
Group | Bupropion, n/N (%) | Placebo, n/N (%) | Odds Ratio (95% CI) |
All subjects | 17/3,179 (0.53) | 11/2,310 (0.48) | 1.28 (0.59–2.86)a |
Age group | |||
18–24 y | 5/324 (1.54) | 3/236 (1.27) | 1.22 (0.28–6.24) |
25–64 y | 12/2,542 (0.47) | 7/1,818 (0.39) | 1.23 (0.48–3.32) |
≥ 65 y | 0/313 (0.0) | 1/255 (0.39) | 0.0 (0.0–15.48) |
Missing | 0/0 (0.0) | 0/1 (0.0) | … |
Gender | |||
Female | 11/1,957 (0.56) | 8/1,444 (0.55) | 1.01 (0.40–2.65) |
Male | 6/1,222 (0.49) | 3/866 (0.35) | 1.42 (0.35–6.96) |
P = .566.