Table 3.
Incidence of Suicidal Behavior by Treatment Group and Subgroup in the Major Depressive Disorder Population
| Group | Bupropion, n/N (%) | Placebo, n/N (%) | Odds Ratio (95% CI) |
| Overall | 8/3,179 (0.25) | 2/2,310 (0.09) | 3.52 (0.81–24.48)a |
| Age group | |||
| 18–24 y | 3/324 (0.93) | 2/236 (0.85) | 1.09 (0.16–9.25) |
| 25–64 y | 5/2,542 (0.20) | 0/1,818 (0.0) | inf (0.87–inf) |
| ≥ 65 y | 0/313 (0.0) | 0/255 (0.0) | … |
| Missing | 0/0 (0.0) | 0/1 (0.0) | … |
| Gender | |||
| Female | 5/1,957 (0.26) | 1/1,444 (0.07) | 3.70 (0.51–88.01) |
| Male | 3/1,222 (0.25) | 1/866 (0.12) | 2.13 (0.23–56.11) |
a
P = .115.
Abbreviation: inf = infinity.