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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Pharmacol Ther. 2010 Oct 15;129(2):149–171. doi: 10.1016/j.pharmthera.2010.09.007

Figure 2. Social interaction after withdrawal from alcohol (ET) re-exposure of rats previously exposed to repeated cycling of alcohol.

Figure 2

Animals were given three cycles of 5 days of 7% alcohol diet (ED-CY3) followed by an additional 5 days of alcohol diet 8 or 16 days after the initial repeated alcohol exposure (ED-CY3-R-8D & ED-CY3-R-16 D). CD rats received only control diet. The CY1 is withdrawal from a single cycle of alcohol diet to animals that previously received CD. Social interaction as a measure of anxiety-like behavior was measured 5–6 hrs after withdrawal from the re-exposure to alcohol diet. * P < 0.01 compared to CD and CY1. Modified from Overstreet et al. (2002) by permission of publisher.

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