Table 2.
SNP | Gene Location |
Major allele |
Minor allele |
Burdick 2006 |
Stefanis 2007 |
Zinkstok 2007 |
Luciano 2009: Scottish |
Luciano 2009: Australian |
Luciano 2009: English |
Kircher 2009 | Hashimoto 2009 |
Peters 2008 |
Need 2009 |
# samples |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
rs1047631 | UTR | A* | G | X | X | X | 3 | |||||||
rs909706 | Intron | G | A | X | X | X | X | 4 | ||||||
rs1018381 | Intron | C* | T | X | X | X | X | X | X | X | Xa | 8 | ||
rs2619522 | Intron | T* | G | X | X | X | X | X | X | X | 7 | |||
rs760761 | Intron | C* | T | X | X | X | X | Xb | 5 | |||||
rs3213207 | Intron | A* | G | X | X | X | X | X | 5 | |||||
rs1011313 | Intron | G* | A | X | X | X | X | X | X | X | X | 8 | ||
rs2619539c | Intron | G | C | X | X | X | X | X | 5 | |||||
rs2619538 | 5′ flanking region |
T | A | X | X | X | 3 | |||||||
N | 126 | 2243 | 62 | 1054 | 1806 | 745 | 518 | 165 | 172 | 701 | 7592 |
Data was from rs11753919 on Illumina, which is a perfect proxy for rs1018381.
Data was from rs1474605 on Illumina, which is a perfect proxy for rs760761.
According to HapMap, the G allele (+ strand) is the major allele in Caucasians, but not in Japanese subjects. However, for consistency, the G allele (+ strand) homozygotes were compared to C allele (+ strand) carriers in all studies, including that of Hashimoto et al. 2009.
SNPs were genotyped off the – strand.