Table 3.

Risk Factors for Presence of Coronary Artery Calcified Plaque in the Combined Cohort of Persons with Diabetes

	MODEL 1 Adjusted for Age, Study, Race, Sex, and Race X Sex			MODEL 2 Fully Adjusted Model *
	Odds Ratio	95% Confidence interval	p-value	Odds Ratio	95% Confidence interval	p-value
Age (yrs) For 10 years	2.14	[1.89,2.42]	<0.0001	2.26	[1.94,2.64]	<0.0001
Race X Sex (ref., white males)	Black female: 0.18	[0.09,0.38]	<0.0001	Black female: 0.16	[0.07,0.39]	<0.0001
	Black male: 0.27	[0.18,0.40]		Black male: 0.26	[0.16,0.42]
	White female: 0.30	[0.21,0.44]		White female: 0.31	[0.20,0.49]
Study (ref., MESA)	DHS: 3.07	[2.31,4.07]	<0.0001	DHS: 2.59	[1.86,3.61]	<0.0001
	FHS: 2.53	[1.75,3.65]	<0.0001	FHS: 2.63	[1.75,3.93]	<0.0001
HbA1c (%) †	1.11	[1.04,1.20]	0.002	1.11	[1.02,1.2]	0.02
Duration of diabetes (yrs) For 10 years	1.28	[1.09,1.50]	0.001	1.36	[1.15,1.61]	0.0003
LDL (mg/dl) For 20 mg/dl	1.07	[1.00,1.15]	0.049	1.12	[1.03,1.19]	0.005
HDL (mg/dl) For 15 mg/dl	0.94	[0.83,1.06]	0.33	0.95	[0.81,1.10]	0.48
TG (mg/dl) For 135 mg/dl	1.06	[0.94,1.19]	0.34	0.95	[0.73,1.23]	0.68
CRP ((mg/l)) For 10 mg/dl	1.30	[0.45,3.71]	0.63	0.96	[0.86,2.68]	0.41
Pack-years For 10 pack-yrs	1.10	[1.03,1.17]	0.002	1.08	[1.03,1.16]	0.005
Current smoker (ref., non-smoker)	1.86	[1.36,2.56]	<0.001	1.80	[1.21,2.67]	0.004
Hypertension	1.41	[1.07,1.86]	0.02	1.33	[0.97,1.83]	0.08
BMI (kg/m2)	1.02	[1.00,1.04]	0.02	1.02	[1.00,1.25]	0.04

^*Fully adjusted model includes age, study, race, sex, race X sex, duration of diabetes, LDL, HDL, TG, pack-years, current smoker, hypertension, CRP, and BMI.

^†Models of HbA1c are restricted to the MESA and DHS studies.