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p38 phosphorylation after 2 or 14 days of saline or isoproterenol treatment in (A) wildtype and Fgf2 knockout (-/-) mouse hearts and (B) non-transgenic and FGF2 transgenic (Tg) mouse hearts. There is no significant difference in the phosphorylation state of p38 in any treatment group suggesting p38 is not activated at these time points in this model of isoproterenol-induced hypertrophy. *p<0.05 vs. saline treatment, +p<0.05 vs. wildtype, n=4–10 for each group.
