Relative expression of CAV1, MSN, IGFBP2, and STAT1 in association with Stat and Akt protein phosphorylation in LA-SCCHN. Tumors were categorized as positive/negative for phosphorylated Stat1-Y701, Stat3-Y705, Stat5-Y694, Akt-T308, and Akt-S473. RQ values are shown in a logarithmic scale. Horizontal lines correspond to mean values per category. Categories (IHC status, x axis) in the lower graph are valid for all graphs. Statistically significant associations of gene expression with Stat/Akt phosphorylation status are shown (Mann-Whitney P, exact significance, two-sided).