Figure 7.
Structure and function of alginate lyases. (A) Active site in A1-III complexed with unsaturated alginate tetrasaccharide. (B) Removal of alginate biofilm by A1-III (left, P. aeruginosa cells covered with biofilm; right, P. aeruginosa cells exposed after treatment with A1-III). (C) Active site in A1-II' complexed with unsaturated alginate tetrasaccharide.