Table 2.
Relationship of serum inflammatory mediators to levels of serum antibody in the baboons at each time-point of the study
| Inflammatory analyte | Baseline | Mid-pregnancy | Delivery |
|---|---|---|---|
| CRP | 0·621 | n.s. | n.s. |
| Pg↑, En↑, Ec↓ | |||
| PGE2 | n.s. | n.s. | n.s. |
| IL-6 | n.s. | 0·452 | 0·573 |
| Fn↑, Pg↑, Mm↓ | Aa↑, Cr↓ | ||
| IL-8 | 0·607 | 0·562 | n.s. |
| Aa↑, Fn↑, Cr↓, An↓ | Pg↑, Fn↑, Tf↓ | ||
| MCP-1 | 0·545 | 0·453 | n.s. |
| Aa↑, Pn↑, Cr↓,Sg↓ | Aa↑, Fn↑, Ec↓, An↓ | ||
| RANTES | n.s. | n.s. | n.s. |
| BPI | n.s. | n.s. | n.s. |
| LBP | 0·457 | n.s. | n.s. |
| Cr↑, Pg↓, Fn↓, |
The numbers denote an adjusted R2 value. The arrows denote the direction of antibody relationship to the mediator. BPI, bactericidal permeability inducing factor; CRP, C-reactive protein; IL, interleukin; LBP, lipopolysaccharide binding protein; MCP, macrophage chemotactic protein; n.s., no significant relationship between antibody and any of the mediators; PGE2, prostaglandin E2; RANTES, regulated upon activation, normal T cell expressed and secreted.