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Paper spray ionization. (a) A typical operation process of applying paper spray for analysis of a dried blood spot and the comparison of sprays between paper spray and nano-ESI. Adapted with permission from ref. 13. (b) Analysis of therapeutic drug in dried blood spot, MS and MS/MS analysis of 400 pg atenolol and 20 pg atenolol, respectively, in 0.4 uL blood. Adapted with permission from ref. 14.
