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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: Biol Psychiatry. 2010 Dec 15;68(12):1172–1181. doi: 10.1016/j.biopsych.2010.09.022

Figure 5.

Figure 5

Molecular markers of interactions

(A) Representative blots for mhDISC1, endogenous DISC1 (eDISC1) and GSK-3β from cortical samples collected at P2;

(B) Prenatal immune activation significantly increased levels of mhDISC1, n=6–7 samples per group, * denotes p<0.05 vs. saline-treated mhDISC1 mice;

(C) Prenatal immune activation significantly decreased levels of endogenous DISC1 in mhDISC1 mice, n=6–7 samples per group, # denotes p<0.05 vs. saline-treated mutant mice;

(D) Prenatal stimulation significantly decreased levels of GSK-3β in control mice but not in mhDISC1 mice, n=6–7 samples per group, * denotes p<0.05 vs. saline-treated control mice.