Figure 2. Systemic MB reduced the size of the histological damage produced by AZ.
Representative photomicrographs of comparable Nissl-stained sections at the level of the AZ injection sites in the PCC to illustrate primary histological data. A) Control brain. Section from a sham operated rat not receiving any injections into the PCC, illustrating normal histology. B) Control vehicle-injected brain. Section from a sham operated rat receiving bilateral vehicle injections into the PCC, illustrating minimal effects on the histology. C) AZ injected brain. Section from an operated rat that received bilateral AZ injections into the PCC, illustrating discoloration and tissue damage on the PCC histology. D) AZ+MB injected brain. Section from an operated rat that received bilateral AZ injections into the PCC plus systemic MB, illustrating attenuated AZ effects on the histology of the PCC.