Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Characterization of 64Cu Labeled Peptides
| Peptide | RP-HPLC (tr-min) | Labeling yield (%) | Radiochemical purity | Receptor affinity (IC50, nM) |
|---|---|---|---|---|
| 64Cu-DO3A-GSG-KCCYSL | 12.8 | 55 | ≥98 | 42 ± 10.2 |
| 64Cu-CB-TE2A-GSG-KCCYSL | 13.3 | 45 | ≥98 | 31 ± 7.9 |
| 64Cu-NO2A-GSG-KCCYSL | 13.0 | 57 | ≥98 | 44 ± 6.6 |
The IC50 was determined using corresponding nonradiolabeled counterparts. Details are given in Materials and Methods section.
IC50, 50% inhibitory concentration; RP-HPLC, Reverse phase-high performance liquid chromatography.
