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. 2011 Jan 25;121(2):593–603. doi: 10.1172/JCI41062

Figure 12. NAC has no effect on bleeding times in mice.

Figure 12

Tail-vein bleeding times were examined in 6- to 8-week-old wild-type C57BL/6 mice. Either PBS (control) or NAC (0.8 mg/g) was administered through the tail vein 30 minutes or 8 hours before the bleeding time was determined. Data represent mean ± SEM. The number of mice examined in each group was 5 for A and 10 for B. No significant differences in bleeding times were observed between treated and untreated mice. The data were analyzed using the Mann-Whitney nonparametric procedure. The adjusted P values for the comparisons between control and NAC-treated animals were 0.47 and 0.86, for the 30 minute and 8 hour analyses, respectively.