Figure 2. Effect of NAC on platelet–vWF strings under flow.

(A) Platelets adherent to vWF strings secreted from, and anchored to, histamine-stimulated HUVECs are marked with arrows. (B) Quantification of the platelet-vWF strings. The number of platelet-vWF strings after perfusion with 40 mM NAC was 23% of the untreated control (P < 0.001). Mean values of string number with SD from 5–9 experiments are shown. The data were analyzed using Student’s t test.