Figure 6. Mouse CD200^hiItga6^hi cells are multipotent and capable of reconstituting a hair follicle.

(A–D) Stereoscopic images of grossly dissected subcutaneous cysts from SCID mouse hosts after injection of sorted cells isolated from ROSA26 mice that constitutively express β-galactosidase, which allows for development of blue color. Hair follicle regeneration from injected CD200^hiItga6^hi cells (A and B) appeared greater than that from CD200^–Itga6^hi cells (C and D). (E) Quantitation of the number of blue hairs originating from sorted cells demonstrated a greater number of de novo hair follicles in CD200^hiItga6^hi compared with CD200^–Itga6^hi cells in 2 subsequent independent repeat experiments.