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. 2011 Jan 18;121(2):582–592. doi: 10.1172/JCI44907

Figure 1. Lineage analysis of donor- and host-derived leukocytes in congenic recipients.

Figure 1

Multilineage engraftment of FL-derived hematopoietic cells was seen in primary (thymus and BM) and secondary (spleen and lymph node [LN]) lymphoid organs and peripheral blood at 43–57 weeks after in utero transplantation (n ≥ 5 mice per group). Donor- and host-derived double-positive (DP: CD4+CD8+) and single-positive (SP: CD4+CD8– or CD4–CD8+) thymocytes, T lymphocytes (T, CD4, and CD8), B lymphocytes (B), and granulocytes (Gr) are shown as a percentage of their respective CD45+ leukocyte gate (donor, CD45.1; host, B6; CD45.2). No significant differences were observed between the percentages of donor and host leukocyte subpopulations, with the exception of a decreased percentage of donor-derived B cells in spleen. *P < 0.05 by t test.