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. 2011 Jan 25;6(1):e16141. doi: 10.1371/journal.pone.0016141

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Zúñiga et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The error bars represent the standard error of the free energy difference at each z in the final free energy profile. A, The free energy profile of system with the R224 residues neutralized in both monomers (black line) and the charged-charged situation (red line). B, Free energy profile of system with neutral-R224⁰-A224 state of TASK-2 (black line) and charged R224⁺-A224 state (red line).