Figure 3. Biofilm formed by the bcr1/bcr1 mutant, complemented and reference (DAY185) strains on a three-dimensional organotypic model of the oral mucosa.

Histologic pictures show 40× magnification after 6 and 24 hours of inoculation. Thin sections were stained with PAS. Arrows indicate biofilms forming on the (apical) epithelial surface of the cultures. Results are representative of one of three experiments.