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. 2011 Jan 25;6(1):e16218. doi: 10.1371/journal.pone.0016218

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Dwivedi et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Susceptibility was tested on 96 well plates (A,B) or on a three dimensional model of the human oral mucosa (C). Strains were exposed to differentiated HL-60 cells (A,C) or freshly isolated neutrophils from one human donor (B) at an effector to target cell ratio of 1∶1 (A,B) or 10∶1 (C). Results represent the mean ± SD of three experiments, each condition set up in triplicate. *p<0.03 and **p<0.05 for a comparison between the bcr1/bcr1 mutant and HYR1- overexpressing strain in the bcr1/bcr1 background.