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. Author manuscript; available in PMC: 2012 Mar 1.
Published in final edited form as: Genes Brain Behav. 2010 Oct 19;10(2):186–198. doi: 10.1111/j.1601-183X.2010.00654.x

Figure 2. Motor activity [A: Horizontal; B: Rearing Responses] of Bdnf+/− and WT mice at 15-minute intervals during one-hour open-field activity tests at 3, 15, and 21 months of age.

Figure 2

Both Distance Traveled, Fig 2A, and Rearing Response frequency, Fig 2B, declined across the hour session. The only effect of the Genotype or Age on the decline in activity across the tests was an Age by Interval interaction for the Rearing Response measure with the decline more rapid for older mice. Both Distance Traveled and Rearing Responses declined with age. The Genotype factor was associated with reductions in Rearing Response frequency; however, did not impact Distance Traveled. Finally, the apparent difference in the pattern of change in Distance Traveled across age for the two genotypes suggested by Fig 2A reached only a 0.09 level of significance.