Table 4.

The ADH7 haplotype block: haplotype frequencies in alcoholics and controls

Haplotype Blocks	Plains Indians		Southwest Indians		Finnish Caucasians		African Americans
Intergenic Block	AD	Controls	AD	Controls	AD	Controls	AD	Controls
11	0.38	0.34	0.29*	0.38	0.76	0.72	0.83	0.86
22	0.63	0.66	0.71*	0.63	0.24	0.28	0.16	0.14
ADH7 Block
212111	0.31	0.32	0.63	0.65	0.27	0.26	0.14	0.12
111122	0.21	0.20	0.03	0.03	0.01	0.01	0.16	0.15
111222	0.03	0.04	0.04	0.04	0.12	0.13	0.03	0.02
122122	0.46	0.45	0.29	0.28	0.53	0.52	0.47	0.48
122111					0.06	0.08
112122							0.15	0.15
§N	448	218	634	144	462	388	534	844

The table lists haplotypes that have a frequency ≥ 5% in at least one population.

^§N: the number of haplotypes. AD = alcohol dependence

^*P value < 0.05.

Intergenic block includes SNPs 32-33, ADH7 block includes SNPs 35-40 as listed in Table1. SNP 34 (rs1154454) is not in either haplotype block.