Table 2.
CSI and TALOS-based torsion angle data for GNNQQNY fibrils. Some of these data were previously reported (30). Asterisks indicate data at the termini of the peptide that are unsuitable for TALOS analysis, since it relies on triplets of residues. The data for Asn-9 in fibril form #2 were inconclusive (marked with X; see also Figure S5). More CSI data analysis is included in the SI (fig. S4).
| residue | Fibril form 1 | Fibril form 2 | Fibril form 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| TALOS | CSI | TALOS | CSI | TALOS | CSI | ||||
| ϕ | ψ | ϕ | ψ | ϕ | ψ | ||||
| G7 | * | * | β | * | * | β | * | * | β |
| N8 | −108 ±20 | 127 ±10 | β | 54 ±6 | 40 ±13 | α | −119 ±18 | 131 ±12 | β |
| N9 | −101 ±11 | 131 ± 13 | β | −88 ±22 | X | α | −116 ±19 | 128 ± 8 | β |
| Q10 | −131 ±14 | 151 ±13 | β | −142 ±13 | 156 ±10 | β | −146 ±15 | 155 ±15 | β |
| Q11 | −150 ±12 | 149 ±12 | β | −129 ±22 | 132 ±11 | β | −145 ±12 | 153 ±9 | β |
| N12 | * | * | β | * | * | β | * | * | β |