Figure 2.

Manumycin affects motility and is toxic to C. elegans. (A) Relative motility of control and manumycin-treated worms. Black bars indicate control; dark gray bars 125 nM manumycin and light gray bars 250 nM of manumycin. Y-axis shows relative average motility to control worms at day 1 of adulthood. (B) Survival plot of control and manumycin treated animals. The amount of manumycin is indicated next to each graph. The animal lifespan was shortened with increased doses of manumycin.