Figure 1.
Apomorphine induced rotational behaviour in experimental rats. Adult male Wistar rats were intranigrally infused with 6-OHDA (8 μg in 1 μl). Bone marrow cell and neurotransmitters were infused individually and in combination in denervated striatum on the 18th day. Animals were injected with apomorphine (1 mg/kg; s.c.) on the 30th day and the apomorphine-induced rotations were recorded for every 10 min duration for a period of 70 min. Values are Mean ± S.E.M of 4-6 separate experiments. Each group consist 6-8 rats. a p < 0.001, b p < 0.01, c P < 0.05 when compared to Control. d p < 0.001, e p < 0.01 when compared to 6-OHDA group.