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. 1993 Jan;61(1):335–337. doi: 10.1128/iai.61.1.335-337.1993

Binding of pertussis toxin to lipid vesicles containing glycolipids.

S Z Hausman 1, D L Burns 1
PMCID: PMC302725  PMID: 8418057

Abstract

The binding of pertussis toxin and its B oligomer to lipid vesicles containing glycosphingolipids was studied. Both pertussis toxin and the B oligomer bound to lipid vesicles containing ganglioside GD1a. Binding of pertussis toxin to these vesicles decreased upon treatment of the vesicles with neuraminidase, suggesting that sialic acid residues are important for efficient binding of the toxin to GD1a.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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