Skip to main content
. Author manuscript; available in PMC: 2012 Feb 11.
Published in final edited form as: J Chromatogr A. 2010 Nov 16;1218(6):763–777. doi: 10.1016/j.chroma.2010.11.009

Table 8.

Effect of Column Type on Efficiency, Sample Loading Capacity, and Retention of Basic Drugs.

HC-COOHb Ace C18c N0(HC-COOH) / N0(Ace C18) w1/2(HC-COOH) / w1/2(Ace C18)
Solutesa k' N0d w1/2 (nmol)e r2f k' N0d w1/2 (nmol)e r2f
Methamphetamine 5.12 3680 77.4 0.885 3.90 2950 3.4 0.997 1.25 22.7
MDMA 5.58 3450 26.9 0.987 4.19 2980 3.0 1.000 1.16 9.1
MDA 4.21 3430 89.7 0.968 3.38 2960 3.0 0.999 1.16 30.2
Methcathinone 3.79 3490 190.0 0.978 2.21 2730 9.9 0.992 1.28 19.2
MDEA 6.56 3310 34.9 0.998 6.56 3110 5.0 1.000 1.06 7.0
a

Structures of the basic solutes are shown in Fig. 2.

b

The chromatographic conditions are the same as in Fig. 12.

c

The chromatographic conditions are the same as in Fig. 12.

d

The limiting plate count calculated from Eq. (7) using the corresponding data given in Fig. 12.

e

The sample loading capacity calculated from Eq. (7) using the corresponding data given in Fig. 12.

f

The squared correlation coefficient of the fits based on the data in Fig. 12.