Table 2. Frequencies (%) of the CR polymorphism T16189C and the poly-C tract in cases and controls as well as the corresponding Odds Ratios and 95% Confidence Intervals.
Controls | CADa | P-Valuec(Pearson chi-square test) | ORd(95% CIe) | aORf(95% CIe) | T2DMb | P-Valuec(Pearson chi-square test) | ORd(95% CIe) | aORf(95% CIe) | |
n = 1481 | n = 482 | n = 505 | |||||||
T16189C | 11.8 | 21.6 | <0.0000001 | 2.05 (1.6–2.7) | 2.17 (1.5–3.1)*** | 19.4 | <0.00005 | 1.80 (1.4–2.4) | 1.46 (1.0–2.2) |
Poly-C tract | 9.1 | 15.8 | <0.00005 | 1.87 (1.4–2.5) | 1.61 (1.1–2.5)* | 15.4 | <0.0001 | 1.82 (1.4–2.5) | 1.45 (0.9–2.3) |
CAD = coronary artery disease.
T2DM = type 2 diabetes mellitus.
P-value: compared to controls.
OR = Odds Ratio.
CI = Confidence Interval.
adjusted for age, sex and body mass index.
*p<0.05, p>0.01.
***p<0.001.