Table 3. Frequencies (%) of the CR polymorphism T16189C and the poly-C tract in patients with coronary artery disease from Graz and Salzburg and controls as well as the corresponding Odds Ratios and 95% Confidence Intervals.
Controls | CADa Graz | P-Valueb(Pearson chi-square test) | ORc(95% CId) | aORe(95% CId) | CADa Salzburg | P-Valueb(Pearson chi-square test) | ORc(95% CId) | aORe(95% CId) | |
n = 1481 | n = 191 | n = 291 | |||||||
T16189C | 11.8 | 22.0 | <0.0001 | 2.10 (1.4–3.1) | 2.17(1.4–3.3)*** | 21.3 | <0.00005 | 2.02 (1.5–2.8) | 2.08 (1.1–3.9)* |
Poly-C tract | 9.1 | 14.7 | <0.05 | 1.71 (1.1–2.7) | 1.58 (1.0–2.5) | 16.5 | <0.0005 | 1.97 (1.4–2.8) | 1.58 (0.8–3.2) |
CAD = coronary artery disease.
P-value: compared to controls.
OR = Odds Ratio.
CI = Confidence Interval.
adjusted for age, sex and body mass index.
*p<0.05, p>0.01.
***p<0.001.