Table 4. Frequencies (%) of the CR polymorphism T16189C and the poly-C tract in cases and controls with mitochondrial haplogroups other than T as well as the corresponding Odds Ratios and 95% Confidence Intervals.
Subjects with haplogroups other than T | Controls | CADa | P-Valuec(Pearson chi-square test) | ORd(95% CIe) | aORf(95% CIe) | T2DMb | P-Valuec(Pearson chi-square test) | ORd(95% CIe) | aORf(95% CIe) |
n = 1355 | n = 411 | n = 455 | |||||||
T16189C | 10.5 | 19.0 | <0.00001 | 2.00 (1.5–2.7) | 1.95 (1.3–3.0)** | 16.5 | <0.001 | 1.69 (1.2–2.3) | 1.38 (0.8–2.3) |
Poly-C tract | 8.7 | 17.0 | <0.000005 | 2.15 (1.6–3.0) | 2.03 (1.3–3.2)** | 15.2 | <0.0001 | 1.87 (1.4–2.6) | 1.46 (0.9–2.4) |
CAD = coronary artery disease.
T2DM = type 2 diabetes mellitus.
P-value: compared to controls.
OR = Odds Ratio.
CI = Confidence Interval.
adjusted for age, sex and body mass index.
**p<0.01, p>0.001.