Table 5. Frequencies (%) of the CR polymorphism T16189C and the poly-C tract in patients with type 2 diabetes from Graz and Salzburg and controls as well as the corresponding Odds Ratios and 95% Confidence Intervals.
| Controls | T2DMaGraz | P-Valueb(Pearson chi-square test) | ORc(95% CId) | aORe(95% CId) | T2DMa Salzburg | P-Valueb(Pearson chi-square test) | ORc(95% CId) | aORe(95% CId) | |
| n = 1481 | n = 226 | n = 279 | |||||||
| T16189C | 11.8 | 20.8 | <0.0005 | 1.96 (1.4–2.8) | 3.45 (1.4–8.3)** | 18.3 | <0.005 | 1.67 (1.2–2.4) | 1.33 (0.8–2.1) |
| Poly-C tract | 9.1 | 15.0 | <0.01 | 1.77 (1.2–2.6) | 2.05 (0.7–5.6) | 15.8 | <0.001 | 1.87 (1.3–2.7) | 1.43 (0.9–2.4) |
a
T2DM = type 2 diabetes mellitus.
b
P-value: compared to controls.
c
OR = Odds Ratio.
d
CI = Confidence Interval.
e
adjusted for age, sex and body mass index.
**p<0.01, p>0.001.