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. 2011 Jan 26;6(1):e16503. doi: 10.1371/journal.pone.0016503

Figure 2. Histopathology of spleen and liver from AHSV-4 infected IFNAR −/− mice.

Figure 2

Liver and Spleen. Hematoxylin-eosin staining. Representative examples of the microscopic lesions found on liver and spleen of AHSV-4 infected IFNAR −/− mice are shown. Spleen and liver samples were collected from IFNAR −/− mice, on day 7 post-infection with AHSV-4. The spleen shows loss or its normal structure (a) and abundant deposits of amyloid (a,b). The liver presents a mononuclear inflammatory infiltrate in the portal triad (c) and foci of necrosis (d).