Figure 2. Vestibular function anomaly in Slitrk6-KO mice.
(A) Dynamic characteristics of horizontal optokinetic response (hOKR) of WT (n = 9) and Slitrk6-KO (n = 9) mice. (B) Horizontal vestibulo-ocular reflex (hVOR). There were no differences in gains (left) or phases (right) between WT (n = 9) and KO (n = 9) in hVOR or hOKR. (C) Vertical vestibulo-ocular reflex (vVOR) of WT (n = 8) and Slitrk6-KO mice (n = 6). Gains of vVOR (left) of the Slitrk6-KO mice were significantly smaller than those of WT. (D) Rota- rod test. Rotation indicates the speed of rotation (rpm) at which the mice fell off or revolved around the rod. The values were comparable between WT (n = 12) and Slitrk6-KO (n = 8) mice, suggesting that there were no strong deficits of balancing function in Slitrk6-KO mice. Values are mean ± standard error of the mean.